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ANTI-ASTHMATIC MEDICINE

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COGVGARD Inhaler

COGVGARD Inhaler The Algorithm Of Asthma Management Composition : Tritropium Bromide 9mcg Per Actuation Form : Inhaler / Pack : 1X1’s / Type : 120 Metered Doses Description : In large randomized clinical trials enrolling patients with moderate to severe asthma, add-on therapy with Tiotropium has demonstrated to be efficacious in improving lung function, decreasing risk of exacerbation and slowing the worsening of disease In view of the numerous ancillary effects acting on inflammation, airway remodeling, mucus production and cough reflex, along with the good safety profile and the broad spectrum of efficacy demonstrated in different disease phenotypes, tiotropium can represent a beneficial alternative in the therapeutic management of poorly controlled asthma - Multidiscip Respir Med 12, 12 (2017).

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AXODIL-LB Respule

AXODIL-LB Respule Levosalbutamol 1.25mg + Budesonide 0.5mg Activation of β2 adrenergic receptors on airway smooth muscle leads to the activation of adenylate cyclase and to an increase in the intracellular concentration of cyclic AMP resulting the activation of protein kinase A, which in turn, inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, Hence causes muscle relaxation. Levosalbutamol being a functional short-acting β2 adrenergic receptor agonist, relaxes the smooth muscles from the trachea to the terminal bronchioles. Increased cyclic AMP concentrations are also associated with the inhibition of the release of mediators from mast cells in the airways, irrespective of the spasmogen involved, thereby protecting against all bronchoconstrictor challenges. Budesonide is a potent glucocorticoid that binds with high affinity to the glucocorticoid receptor. It has a high ratio of topical to systemic activity. Budesonide is used to control and prevent symptoms such as wheezing, shortness of breath caused by asthma. Used as maintenance treatment of asthma and as a prophylactic therapy.

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VODARYL Respules

VODARYL Respules Budesonide 0.5mg Respules Budesonide is a potent glucocorticoid that binds with high affinity to the glucocorticoid receptor. It has a high ratio of topical to systemic activity. Budesonide is used to control and prevent symptoms such as wheezing, shortness of breath caused by asthma. Used as maintenance treatment of asthma and as a prophylactic therapy in children 12 months to 8 years of age.

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Vodaryl-FB Inhaler

Vodaryl-FB Inhaler Formoterol is a very potent, long-acting, beta2 adrenoceptor-agonist with a high intrinsic activity and a rapid onset of action Where as Budesonide is a potent glucocorticoid that binds with high affinity to the glucocorticoid receptor. It has a high ratio of topical to systemic activity. The combination medicine has different modes of action and show additive effects in terms of reduction of asthma exacerbations thus used to control and prevent the symptoms of asthma in adults and children above 6 years old. Formoterol & Budesonide is also used to help control the symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis.

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